You can buy Orlistat (Xenical/Alli) as an over-the-counter alternative to Wegovy in the UK.
However, Orlistat is a very different type of weight-loss medication, and research suggests it’s not as effective as Wegovy in supporting weight loss.
Wegovy and Orlistat are weight-loss medications approved for use in the UK. However, they are different medications with distinct dosing schedules, costs, and mechanisms of action on the body.
Orlistat is a lipase inhibitor. Lipases are gut enzymes that break down fat from food, enabling the gut to transport fat into the body to be burnt for energy or stored in our fat cells for later use.
Orlistat blocks lipases, preventing some of the dietary fat from our meals from being digested. This leads to fewer calories being absorbed, which can support weight loss.
Orlistat is a prescription medication produced by two pharmaceutical companies in the UK:
Wegovy is a weight-loss jab manufactured by Novo Nordisk. It’s a weekly weight-loss injection with semaglutide as the active ingredient.
Semaglutide is a that helps reduce hunger and appetite, allowing you to eat fewer calories, lose weight, and manage your blood sugar levels.
Wegovy is approved in the UK for individuals living with obesity to help them eat fewer calories and lose weight.
The over-the-counter version of Orlistat will cost around £18 a month, so it’s a very affordable medication.
In comparison, buying Wegovy and the injectable pens required for four weeks from Second Nature will cost £229 a month, rising to £299.
Orlistat is an affordable medication that is generally well-tolerated. However, it’s less effective than Wegovy. Wegovy is twice as effective as Orlistat for weight loss after one year.
So, if you’re looking for the most affordable weight-loss pill you can purchase over the counter, then Orlistat could be an option.
However, if you have a higher budget and are looking for the most effective weight-loss injection in the UK, semaglutide is a better choice.
Semaglutide is designed as an additional tool for weight management and, in most cases, shouldn’t be considered a lifelong medication.
Instead, it should be used to help you kickstart your weight loss and healthy journey while you commit to living a healthier lifestyle.
Ideally, we’d be able to lose weight without medication and lifestyle changes would be enough to support weight loss in the long term.
We’d generally recommend trying Second Nature’s before considering a weight-loss jab.
Changing your habits is the most sustainable way to achieve long-term weight loss, and it’s also less expensive.
At Second Nature, we’ve been trusted by the NHS since 2017 to support people with type 2 diabetes and obesity to lose weight, manage their blood sugar levels, and lead healthier lifestyles for the long term.
In 2022, the NHS in the BMJ that compared the weight loss outcomes of five providers in the National Diabetes Prevention Programme.
Second Nature was more than twice as effective at supporting weight loss than the other four providers.
However, if you’ve decided to try semaglutide (when it’s available) but need support in making positive changes to your lifestyle, Second Nature could be an option for you. But it’s worth noting that we have strict eligibility criteria.
Second Nature has been clinically-utscheied (compet evaluates the clinical trials evidence) in weight-management and metabolic health.Dietary fats are large molecules that need to be broken down before they can be absorbed into the body. They are broken down by enzymes called lipases. That is, lipases play an important role in the digestion of dietary fat. When taken with a meal, Xenical interferes with the activity of these enzymes. This allows about 30% of the fat eaten in the meal to pass through the gut undigested. Therefore, your body cannot store these excess calories as fatty tissue or use them as a source of energy. This helps you to reduce your weight by burning up fat that you are already carrying, maintain your lower weight and minimise any weight regain. Losing even small amounts of weight and keeping it off produces additional health benefits for you, especially when you are at risk for other diseases such as heart disease and diabetes. Xenical can also help to improve risk factors, such as high blood pressure, high cholesterol and high blood sugar. If these are not treated, they could lead to other diseases such as hypertension and diabetes. Xenical should be taken in conjunction with a well-balanced calorie-controlled diet and other appropriate measures such as exercise.Active Ingredients:Xenical does not contain sucrose, gluten, tartrazine or any other azo dyes. Active ingredient - orlistat each Xenical capsule contains 120 mg orlistatInactive ingredients
DirectionsTake 1 capsule with each of the 3 main meals per day. It can be taken during the meal or up to 1 hour after the meal is consumed.Warnings & Disclaimers
*** Please note that this product is a Scheduled Medicine in Western Australia. In order to ensure this product is appropriate and safe for you to use, we would appreciate it if you could respond to the following questions for us.
Who is this product for (Age and gender)?
What were you using this medication to treat?
Has the person used this medication before?
Is the person who will use this product taking any other medications? Please include any herbal or vitamin supplements.
Does the person who will use this product have any medical conditions? Please list any medical conditions.
Please send a reply with your order number after purchase, to. Please note that if we are unable to contact your to verify the appropriateness of this product, your order may be cancelled and you will be refunded in full.
For more information on Scheduled Medicines, please see the link below https://ww2.health.wa.gov.au/Articles/S_T/Sale-and-supply-by-schedule
Active IngredientsEach active ingredient contains a maximum of 3.00 mg orlistat.Active Ingredients
microcrystalline celluloseDisclaimer: this product is not intended to be used to diagnose, treat or prevent any health condition.
EAN:02186506.eAN:02187087. AN:02187087. Key: wth-xenical-18)].
EAN:02240118. AN:02240119. Key: wth-xenical-21)].
Tested with the specific instructions as shown in the table below.For more information on Active Ingredients please see the link below.
Product Name:Xenical 120mg Capsules
Product Type
Inhaled Antifungal Agent
ManufacturerAstraZeneca plc
Prescription medicinePrescribed for Weight Loss, Diabetes Management, High Blood Pressure, Atherosclerosis Management, Obesity Prevention, Malignant Hyperglycemia, Weight Management, Weight Loss Drugs, Metabolic Syndrome, Metabolic Acidosis Prevention, Metabolic Acidosis Management, Metabolic Syndrome Prevention, Metabolic Syndrome and Metabolism Management, Anti-obesity Drugs, Anti-obesity Drugs Combination Drugs, Anti-obesity Drugs Combined with Diethybal, Antifungal Medicine For Skin and Appendages, Anti-obesity Drugs for Skin and Skin Structure, Anti-obesity Drugs Used For Skin and Appendages, Anti-obesity Drugs Used For Skin and Appendages, Anti-obesity Drugs Used For Heart, Liver & Kidney Diseases, Liver Function, Renal, Liver & Kidney Disease, Primary Prevention, Primary Care Drugs, Primary Care Drugs Combined with Other Medications For Skin and Appendages, Anti-obesity Drugs Used For Secondary Prevention, Anti-obesity Drugs Used For Preventive Treatment of Obesity, Anti-obesity Drugs Used For Preventive Treatment of Diabetes, Anti-obesity Drugs Used For Primary Prevention, Anti-obesity Drugs Used For Secondary Prevention, Anti-obesity Drugs Used For Preventive Treatment of Chronic Obstructive Pulmonary Disease, Anti-obesity Drugs Used For Prevention of Severe Skin Infections, Anti-obesity Drugs Used For Prevention of Ulcer Control, Anti-obesity Drugs Used For Prevention of Pregnancy & Lactation, Anti-obesity Drugs Used For Primary Care, Anti-obesity Drugs Used For Primary Care, Anti-obesity Drugs Used For Preventive Treatment of Diabetes, Anti-obesity Drugs Used For Primary Prevention, Anti-obesity Drugs Used For Primary Care, Anti-obesity Drugs Used For Primary Care Combined with Other Medications, Anti-Obesity Drugs Used For Primary Care Treatment, Inhaled Antifungal Capsules Or Inhaled Antifungal Spray For Indications For Weight Loss, Inhaled Antifungal Capsules Or Inhaled Antifungal Spray For Malignant High Blood Pressure Or Atherosclerosis Management, Inhaled Antifungal Capsules Or Inhaled Antifungal Capsule For Prevention of Certain Other Medical Conditions, Anti-Obesity Drugs For Skin and Appendages, Anti-obesity Drugs For Skin and Appendages Combined with Other Medications,
Active ingredients:Hard Gel Capsules 120 mg
Zenon plc
Contains:All prescription medicines
Directions for use:Take with or without food.
Warnings:Only for adult use.lisinopril (Orlistat) should not be used during pregnancy or during infancy. Lisinopril (Zuroxil) should not be used during pregnancy or during infancy. Use with caution in the following populations: children & teenagers (12 and older) as indicated.
Precautions:Inform your doctor or pharmacist if you are allergic to any medicines, or if you have any of the following conditions: heart failure, liver, kidney, or intestinal disease
Contraindications:Lisinopril or other lisinopril-class drugs should not be used in combination with methotrexate. Other medicines for high blood pressure, diabetes, hyperglycemia, and hyperlipidemia should not be used in combination with these medicines, especially if they are taken together.
Special Precautions:Do not use in patients who are hypersensitive to any of the components of Lisinopril. There have been reports of lisinopril-induced lupus nephritis. If you have an allergy to any of the ingredients in Lisinopril, tell your doctor before using this medicine. Do not use with the combination of lisinopril and methotrexate.
Side effects:All medicines may cause side effects.
Salt Composition in both
Salt Composition
Orlistat 120mg(same for both)
You Searched
Strip of 21 capsules
We only sell the best substitute from top brands
Our Recommendation
Slimore 120mg Capsule 10s
Strip of 10 capsules
840+ Customers trust this
WHO GMP Certified
Marketed by
Doctor ApprovedMedicine Comparison
PlatinumRx is dedicated to delivering dependable and trustworthy information to empower our customers. However, the information presented here is solely for general informational purposes and should not be utilized for diagnosing, preventing, or treating health issues. It is not intended to establish a doctor-patient relationship or serve as a substitute for professional medical advice.
Pantosec DSR 30/40mg PR Capsule 10sPantosec 40mg Tablet 10sCipvildin M 500/50mg Tablet 15sAb Rozu 10mg Tablet 10sCipcal D3 60000IU Capsule 4sCipcal 500mg/250IU Tablet 15sDapaquest 10mg Tablet 10sMontecip LC 5/10mg Tablet 10sLipvas 10mg Tablet 10sParacip 650mg Tablet 10sView More
Aerolife inhalation Device 1sAir Space Wit Exhle Valve Device 1sBp Monitor (Omron) Hem 8712 Device 1sContour Plus System 1sDigital Thermometer Mercury Device 1sDuohaler DPI Device 1sIbreathe DPI Inhealer Device 1sMachaler DPI Device 1sMacspacer Device 1sNovopen 4 | Diabetes Monitoring Devices 1s
Yes!! online plays many different roles in play with Xenical 120mg Capsule 10sWe deliver Xenical 120mg Capsule 10s to USA, Canada, Australia, Japan, Israel, France, Australia, Malaysia, New Zealand, Nigeria,entlesee, Zed Health, Amneal, PPI Medical, USA, China, India, England, Spain, Thailand, Russia, Switzerland, Delitzerland, Uganda, Hundreds more and we’ll even add more orders every day.
Stade de France Pharmacy